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Terminology chevron_right Concepts chevron_right 409159000

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Component

409159000

The component that hold information about this concept.

Fully Specified Name (FSN)

Pemetrexed (substance)

Shortest Term

Pemetrexed

Definition Status

900000000000074008 |Necessary but not sufficient concept definition status (core metadata concept)|

Specifies if the concept version is primitive or defined. Set to a descendant of 900000000000444006

Summary

Pemetrexed (substance)

SCTID: 409159000, Primitive, Active

409159000|Pemetrexed (substance)|

en Pemetrexed
en Pemetrexed (substance)

Expression

409159000 |Pemetrexed (substance)|
 <<< 734874007 |Antimetabolite (disposition)| + 
784017009 |Dihydrofolate reductase inhibitor (disposition)| + 
734587005 |Thymidylate synthase inhibitor (disposition)| + 
784021002 |Phosphoribosylglycinamide formyltransferase inhibitor (disposition)| + 
372612001 |Antifolate (substance)| + 
430503006 |Glutamate (substance)| + 
784022009 |Substance with phosphoribosylglycinamide formyltransferase inhibitor mechanism of action (substance)| + 
429660001 |Substance with thymidylate synthase inhibitor mechanism of action (substance)| + 
784020001 |Substance with dihydrofolate reductase inhibitor mechanism of action (substance)|

Diagram

Active

Component help	Language Code help	Type	Term help	Case Significance help	Acceptability	Active
2470970016 - Pemetrexed (en) View
2470970016	en	Synonym (core metadata concept)	Pemetrexed	900000000000448009 \|Entire term case insensitive (core metadata concept)\|	Preferred	True
2464610017 - Pemetrexed (substance) (en) View
2464610017	en	Fully specified name (core metadata concept)	Pemetrexed (substance)	900000000000448009 \|Entire term case insensitive (core metadata concept)\|	Preferred	True

Type help	Destination help	Relationship group help	Characteristic type help	Active
Relationship (11325967024) - 409159000 -> 784017009 (726542003) View
726542003 \|Has disposition (attribute)\|	784017009 \|Dihydrofolate reductase inhibitor (disposition)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (11325968025) - 409159000 -> 430503006 (116680003) View
116680003 \|Is a (attribute)\|	430503006 \|Glutamate (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (11325969022) - 409159000 -> 734587005 (726542003) View
726542003 \|Has disposition (attribute)\|	734587005 \|Thymidylate synthase inhibitor (disposition)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (11325970023) - 409159000 -> 784022009 (116680003) View
116680003 \|Is a (attribute)\|	784022009 \|Substance with phosphoribosylglycinamide formyltransferase inhibitor mechanism of action (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (11325971022) - 409159000 -> 429660001 (116680003) View
116680003 \|Is a (attribute)\|	429660001 \|Substance with thymidylate synthase inhibitor mechanism of action (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (11325972026) - 409159000 -> 784021002 (726542003) View
726542003 \|Has disposition (attribute)\|	784021002 \|Phosphoribosylglycinamide formyltransferase inhibitor (disposition)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (11325973020) - 409159000 -> 784020001 (116680003) View
116680003 \|Is a (attribute)\|	784020001 \|Substance with dihydrofolate reductase inhibitor mechanism of action (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (7653121028) - 409159000 -> 734874007 (726542003) View
726542003 \|Has disposition (attribute)\|	734874007 \|Antimetabolite (disposition)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (2541426024) - 409159000 -> 372612001 (116680003) View
116680003 \|Is a (attribute)\|	372612001 \|Antifolate (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True

Fully Specified Name (FSN)	Shortest Term	Definition Status help	Active
784017009 View
784017009	Dihydrofolate reductase inhibitor (disposition)	Dihydrofolate reductase inhibitor	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
784020001 View
784020001	Substance with dihydrofolate reductase inhibitor mechanism of action (substance)	Dihydrofolate reductase inhibitor	900000000000073002 \|Sufficiently defined by necessary conditions definition status (core metadata concept)\|	True
784021002 View
784021002	Phosphoribosylglycinamide formyltransferase inhibitor (disposition)	Phosphoribosylglycinamide formyltransferase inhibitor	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
784022009 View
784022009	Substance with phosphoribosylglycinamide formyltransferase inhibitor mechanism of action (substance)	Phosphoribosylglycinamide formyltransferase inhibitor	900000000000073002 \|Sufficiently defined by necessary conditions definition status (core metadata concept)\|	True
429660001 View
429660001	Substance with thymidylate synthase inhibitor mechanism of action (substance)	Thymidylate synthase inhibitor	900000000000073002 \|Sufficiently defined by necessary conditions definition status (core metadata concept)\|	True
734587005 View
734587005	Thymidylate synthase inhibitor (disposition)	Thymidylate synthase inhibitor	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
734874007 View
734874007	Antimetabolite (disposition)	Antimetabolite	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
430503006 View
430503006	Glutamate (substance)	Glutamate	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
372612001 View
372612001	Antifolate (substance)	Antifolate	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True

Fully Specified Name (FSN)	Shortest Term	Definition Status help	Active
1217202002 View
1217202002	Pemetrexed diarginine (substance)	Pemetrexed diarginine	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
735172002 View
735172002	Pemetrexed disodium (substance)	Pemetrexed disodium	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True

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