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Terminology chevron_right Concepts chevron_right 409402009

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Component

409402009

The component that hold information about this concept.

Fully Specified Name (FSN)

Substance with epidermal growth factor receptor antagonist mechanism of action (substance)

Shortest Term

Egfr inhibitor

Definition Status

900000000000073002 |Sufficiently defined by necessary conditions definition status (core metadata concept)|

Specifies if the concept version is primitive or defined. Set to a descendant of 900000000000444006

Summary

Substance with epidermal growth factor receptor antagonist mechanism of action (substance)

SCTID: 409402009, Defined, Active

409402009|Substance with epidermal growth factor receptor antagonist mechanism of action (substance)|

en Egfr (epidermal growth factor receptor) inhibitor
en Epidermal growth factor receptor inhibitor
en Substance with epidermal growth factor receptor inhibitor mechanism of action (substance)
en Epidermal growth factor receptor antagonist

Expression

409402009 |Substance with epidermal growth factor receptor antagonist mechanism of action (substance)|
 === 734625009 |Epidermal growth factor receptor antagonist (disposition)| + 
372688009 |Antineoplastic agent (substance)| + 
426265004 |Protein kinase inhibitor (substance)|

Diagram

Active

Component help	Language Code help	Type	Term help	Case Significance help	Acceptability	Active
3637366018 - EGFR antagonist (en) View
3637366018	en	Synonym (core metadata concept)	EGFR antagonist	900000000000017005 \|Entire term case sensitive (core metadata concept)\|	Acceptable	False
4589762016 - EGFR (epidermal growth factor receptor) inhibitor (en) View
4589762016	en	Synonym (core metadata concept)	EGFR (epidermal growth factor receptor) inhibitor	900000000000017005 \|Entire term case sensitive (core metadata concept)\|	Acceptable	True
2471188018 - Epidermal growth factor receptor inhibitor (en) View
2471188018	en	Synonym (core metadata concept)	Epidermal growth factor receptor inhibitor	900000000000448009 \|Entire term case insensitive (core metadata concept)\|	Preferred	True
3520904018 - Substance with epidermal growth factor receptor antagonist mechanism of action (en) View
3520904018	en	Synonym (core metadata concept)	Substance with epidermal growth factor receptor antagonist mechanism of action	900000000000448009 \|Entire term case insensitive (core metadata concept)\|	Acceptable	False
3520734017 - Substance with epidermal growth factor receptor antagonist mechanism of action (substance) (en) View
3520734017	en	Fully specified name (core metadata concept)	Substance with epidermal growth factor receptor antagonist mechanism of action (substance)	900000000000448009 \|Entire term case insensitive (core metadata concept)\|	Preferred	False
4589761011 - Substance with epidermal growth factor receptor inhibitor mechanism of action (substance) (en) View
4589761011	en	Fully specified name (core metadata concept)	Substance with epidermal growth factor receptor inhibitor mechanism of action (substance)	900000000000448009 \|Entire term case insensitive (core metadata concept)\|	Preferred	True
2477410016 - EGFR inhibitor (en) View
2477410016	en	Synonym (core metadata concept)	EGFR inhibitor	900000000000017005 \|Entire term case sensitive (core metadata concept)\|	Acceptable	False
3520637019 - Epidermal growth factor receptor antagonist (en) View
3520637019	en	Synonym (core metadata concept)	Epidermal growth factor receptor antagonist	900000000000448009 \|Entire term case insensitive (core metadata concept)\|	Acceptable	True
2464853015 - Epidermal growth factor receptor inhibitor (substance) (en) View
2464853015	en	Fully specified name (core metadata concept)	Epidermal growth factor receptor inhibitor (substance)	900000000000448009 \|Entire term case insensitive (core metadata concept)\|	Preferred	False

Type help	Destination help	Relationship group help	Characteristic type help	Active
Relationship (13881955026) - 409402009 -> 407312007 (116680003) View
116680003 \|Is a (attribute)\|	407312007 \|Enzyme inhibitor (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	False
Relationship (9663150022) - 409402009 -> 771382006 (116680003) View
116680003 \|Is a (attribute)\|	771382006 \|Substance with receptor antagonist mechanism of action (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	False
Relationship (13881956025) - 409402009 -> 426265004 (116680003) View
116680003 \|Is a (attribute)\|	426265004 \|Protein kinase inhibitor (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (9292775023) - 409402009 -> 766739005 (116680003) View
116680003 \|Is a (attribute)\|	766739005 \|Substance categorized by disposition (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	False
Relationship (5051125026) - 409402009 -> 372917005 (116680003) View
116680003 \|Is a (attribute)\|	372917005 \|Protein-tyrosine kinase inhibitor (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	False
Relationship (7653136025) - 409402009 -> 734625009 (726542003) View
726542003 \|Has disposition (attribute)\|	734625009 \|Epidermal growth factor receptor antagonist (disposition)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (2541717020) - 409402009 -> 372688009 (116680003) View
116680003 \|Is a (attribute)\|	372688009 \|Antineoplastic agent (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True

Fully Specified Name (FSN)	Shortest Term	Definition Status help	Active
426265004 View
426265004	Protein kinase inhibitor (substance)	Protein kinase inhibitor	900000000000073002 \|Sufficiently defined by necessary conditions definition status (core metadata concept)\|	True
734625009 View
734625009	Epidermal growth factor receptor antagonist (disposition)	Egfr antagonist	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
372688009 View
372688009	Antineoplastic agent (substance)	Antineoplastic agent	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True

Fully Specified Name (FSN)	Shortest Term	Definition Status help	Active
1269168000 View
1269168000	Lapatinib ditosylate anhydrous (substance)	Lapatinib ditosylate anhydrous	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
1162751008 View
1162751008	Amivantamab (substance)	Amivantamab	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
784176007 View
784176007	Substance with human epidermal growth factor receptor 2 inhibitor mechanism of action (substance)	Human epidermal growth factor receptor 2 inhibitor	900000000000073002 \|Sufficiently defined by necessary conditions definition status (core metadata concept)\|	True
765360008 View
765360008	Nimotuzumab (substance)	Nimotuzumab	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
734660003 View
734660003	Osimertinib mesilate (substance)	Osimertinib mesilate	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
725960003 View
725960003	Lapatinib ditosylate monohydrate (substance)	Lapatinib ditosylate monohydrate	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
716015005 View
716015005	Necitumumab (substance)	Necitumumab	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
716032009 View
716032009	Osimertinib (substance)	Osimertinib	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
426238006 View
426238006	Lapatinib ditosylate (substance)	Lapatinib ditosylate	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
426686007 View
426686007	Erlotinib hydrochloride (substance)	Erlotinib hydrochloride	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
423259008 View
423259008	Panitumumab (substance)	Panitumumab	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
418260004 View
418260004	Vandetanib (substance)	Vandetanib	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
414123001 View
414123001	Erlotinib (substance)	Erlotinib	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
409400001 View
409400001	Cetuximab (substance)	Cetuximab	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
407100002 View
407100002	Gefitinib (substance)	Gefitinib	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True

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Terminology chevron_right Concepts chevron_right 409402009

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