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Terminology chevron_right Concepts chevron_right 422042001

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Component

422042001

The component that hold information about this concept.

Fully Specified Name (FSN)

Sorafenib (substance)

Shortest Term

Sorafenib

Definition Status

900000000000074008 |Necessary but not sufficient concept definition status (core metadata concept)|

Specifies if the concept version is primitive or defined. Set to a descendant of 900000000000444006

Summary

Sorafenib (substance)

SCTID: 422042001, Primitive, Active

422042001|Sorafenib (substance)|

en Sorafenib
en Sorafenib (substance)

Expression

422042001 |Sorafenib (substance)|
 <<< 734578001 |Angiogenesis inhibitor (disposition)| + 
734581006 |Protein-tyrosine kinase inhibitor (disposition)| + 
786911005 |Vascular endothelial growth factor receptor antagonist (disposition)| + 
409408008 |Angiogenesis inhibitor (substance)| + 
372917005 |Protein-tyrosine kinase inhibitor (substance)| + 
65025001 |Pyridine (substance)| + 
372688009 |Antineoplastic agent (substance)| + 
786910006 |Substance with vascular endothelial growth factor receptor antagonist mechanism of action (substance)| + 
1156664003 |Phenylurea compound (substance)|

Diagram

Active

Component help	Language Code help	Type	Term help	Case Significance help	Acceptability	Active
2618051018 - Sorafenib (en) View
2618051018	en	Synonym (core metadata concept)	Sorafenib	900000000000448009 \|Entire term case insensitive (core metadata concept)\|	Preferred	True
2615384010 - Sorafenib (substance) (en) View
2615384010	en	Fully specified name (core metadata concept)	Sorafenib (substance)	900000000000448009 \|Entire term case insensitive (core metadata concept)\|	Preferred	True

Type help	Destination help	Relationship group help	Characteristic type help	Active
Relationship (9335366029) - 422042001 -> 407312007 (116680003) View
116680003 \|Is a (attribute)\|	407312007 \|Enzyme inhibitor (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	False
Relationship (13814052023) - 422042001 -> 1156664003 (116680003) View
116680003 \|Is a (attribute)\|	1156664003 \|Phenylurea compound (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (13191342027) - 422042001 -> 786911005 (726542003) View
726542003 \|Has disposition (attribute)\|	786911005 \|Vascular endothelial growth factor receptor antagonist (disposition)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (13191343021) - 422042001 -> 786910006 (116680003) View
116680003 \|Is a (attribute)\|	786910006 \|Substance with vascular endothelial growth factor receptor antagonist mechanism of action (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (9309354025) - 422042001 -> 312414008 (116680003) View
116680003 \|Is a (attribute)\|	312414008 \|Chemical categorized functionally (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	False
Relationship (9560873026) - 422042001 -> 372688009 (116680003) View
116680003 \|Is a (attribute)\|	372688009 \|Antineoplastic agent (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (7653427023) - 422042001 -> 734578001 (726542003) View
726542003 \|Has disposition (attribute)\|	734578001 \|Angiogenesis inhibitor (disposition)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (7653428029) - 422042001 -> 734581006 (726542003) View
726542003 \|Has disposition (attribute)\|	734581006 \|Protein-tyrosine kinase inhibitor (disposition)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (2945767022) - 422042001 -> 409408008 (116680003) View
116680003 \|Is a (attribute)\|	409408008 \|Angiogenesis inhibitor (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (2945768028) - 422042001 -> 372917005 (116680003) View
116680003 \|Is a (attribute)\|	372917005 \|Protein-tyrosine kinase inhibitor (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True
Relationship (2945769020) - 422042001 -> 65025001 (116680003) View
116680003 \|Is a (attribute)\|	65025001 \|Pyridine (substance)\|	0	900000000000011006 \|Inferred relationship (core metadata concept)\|	True

Fully Specified Name (FSN)	Shortest Term	Definition Status help	Active
1156664003 View
1156664003	Phenylurea compound (substance)	Phenylurea compound	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
786910006 View
786910006	Substance with vascular endothelial growth factor receptor antagonist mechanism of action (substance)	Vegf antagonist	900000000000073002 \|Sufficiently defined by necessary conditions definition status (core metadata concept)\|	True
786911005 View
786911005	Vascular endothelial growth factor receptor antagonist (disposition)	Vegf antagonist	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
372917005 View
372917005	Protein-tyrosine kinase inhibitor (substance)	Protein-tyrosine kinase inhibitor	900000000000073002 \|Sufficiently defined by necessary conditions definition status (core metadata concept)\|	True
409408008 View
409408008	Angiogenesis inhibitor (substance)	Angiogenesis inhibitor	900000000000073002 \|Sufficiently defined by necessary conditions definition status (core metadata concept)\|	True
734578001 View
734578001	Angiogenesis inhibitor (disposition)	Angiogenesis inhibitor	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
734581006 View
734581006	Protein-tyrosine kinase inhibitor (disposition)	Protein-tyrosine kinase inhibitor	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
372688009 View
372688009	Antineoplastic agent (substance)	Antineoplastic agent	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True
65025001 View
65025001	Pyridine (substance)	Pyridine	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True

Fully Specified Name (FSN)	Shortest Term	Definition Status help	Active
432886002 View
432886002	Sorafenib tosylate (substance)	Sorafenib tosylate	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|	True

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